Glylup M Tablet [Glipizide (NA) + Metformin (NA)]

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glylup M Tablet is to be taken with food.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glylup M Tablet is to be taken with food.

'- Alcohol : UNSAFE

It is unsafe to consume alcohol with Glylup M Tablet.

- Pregnancy : CONSULT YOUR DOCTOR

Glylup M Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

- Breast feeding : CONSULT YOUR DOCTOR

Glylup M Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

- Driving : CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

- Kidney : CAUTION

Glylup M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glylup M Tablet may be needed. Please consult your doctor.Use of Glylup M Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

- Liver : CAUTION

Glylup M Tablet should be used with caution in patients with liver disease. Dose adjustment of Glylup M Tablet may be needed. Please consult your doctor.Glylup M Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

If you miss a dose of Glylup M Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

strip of 10 tablets

Habit Forming :: No
Therapeutic Class :: ANTI DIABETIC

Treatment of Type 2 diabetes mellitus

Store below 30?C

Q. What is Glylup M Tablet?::: Glylup M Tablet is a combination of two medicines: Glipizide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glipizide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.| Q. What are the possible side effects of Glylup M Tablet?::: The use of Glylup M Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.| Q. Can the use of Glylup M Tablet cause hypoglycemia?::: Yes, the use of Glylup M Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you.| Q. Can the use of Glylup M Tablet cause lactic acidosis?::: Yes, the use of Glylup M Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glylup M Tablet and immediately consult your doctor.| Q. Can the use of Glylup M Tablet lead to Vitamin B12 deficiency?::: Yes, the use of Glylup M Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in the hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.| Q. Are there any specific conditions in which Glylup M Tablet should not to be taken?::: The use of Glylup M Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.| Q. Is it safe to take alcohol while I am also taking Glylup M Tablet?::: No, it is not safe to take Glylup M Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.| Q. What are the instructions for storage and disposal of Glylup M Tablet?::: Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.