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In Treatment of Bacterial infections Magnacillin 500 mg/500 mg Injection is a combination of two antibiotics, Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.