Denorange Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.Denorange Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine.Some common side effects of this medicine include headache, pain in extremity, musculoskeletal pain, nerve pain, constipation, and rash. Talk to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

'- Alcohol : CAUTION

Caution is advised when consuming alcohol with Denorange Injection. Please consult your doctor.

- Pregnancy : UNSAFE

Denorange Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

- Breast feeding : CONSULT YOUR DOCTOR

Denorange Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

- Driving : SAFE

Denorange Injection does not usually affect your ability to drive.

- Kidney : CAUTION

Denorange Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Denorange Injection may be needed. Please consult your doctor.

- Liver : CAUTION

Denorange Injection should be used with caution in patients with severe liver disease. Dose adjustment of Denorange Injection may be needed. Please consult your doctor.

If you miss a dose of Denorange Injection, please consult your doctor.

prefilled syringe of 1 ml Injection

Chemical Class :: Monoclonal antibody (mAb)
Habit Forming :: No
Therapeutic Class :: PAIN ANALGESICS

Osteoporosis

Store in a refrigerator (2 - 8?C). Do not freeze.

Q. How long can you stay on Denorange Injection?::: There is no optimal duration of treatment of osteoporosis with Denorange Injection. The patient???s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denorange Injection. Depending on this, the duration of taking Denorange Injection is decided.| Q. Does Denorange Injection cause hair loss?::: Yes, hair loss is a common side effect of Denorange Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.| Q. Is Denorange Injection a chemotherapy drug?::: Denorange Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denorange Injection makes the bones stronger and less likely to break.| Q. How is Denorange Injection given and how often?::: Denorange Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denorange Injection.| Q. Can Denorange Injection be taken during pregnancy?::: No, pregnant women should not take Denorange Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denorange Injection if you can become pregnant.| Q. How should Denorange Injection be stored?::: Denorange Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.| Q. Does Denorange Injection cause osteonecrosis of the jaw?::: Osteonecrosis is a rare side effect of Denorange Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denorange Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

Musculoskeletal (bone, muscle or joint) pain
Pain in extremities
Nerve pain
Constipation
Rash
Headache